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KMID : 1022820180090020044
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Journal of Multiple Sclerosis and Neuroimmunology
2018 Volume.9 No. 2 p.44 ~ p.46
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Neuromyelitis Optica Spectrum Disease with Laboratory Supported Sjogren’s Syndrome
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Rha Hae-Joo
Lee Dong-Kuck
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Abstract
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Neuromyelitis optica spectrum disease (NMOSD) is an idiopathic inflammatory disorder of the central nervous system characterized by extensive longitudinal and transverse myelitis. Although the pathogenesis of NMOSD needs to be elucidated, a reported related antigen is aquaporin 4 (AQP4). Moreover, an AQP-4 Ab seropositive tendency among patients with NMOSD supports the validity of high coexistence of autoimmune diseases such as systemic lupus erythematosus and Sjogren syndrome.
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KEYWORD
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Neuromyelitis optica, Sjogren's syndrome
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